What is NMN?
NMN is short for nicotinamide mononucleotide, a naturally occurring molecule within all species. About the molecular level, it is a ribonucleotide, a fundamental structural unit with the nucleic acid RNA. It is made up of nicotinamide group, a ribose, along with a phosphate group.
NMN is really a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule which might be attractive scaling down some aspects of aging. NAD+ serves many critical functions in our cells, for example electron transport, cell signaling, and DNA repair.
Accumulating evidence implies that as we get older, our amounts of NAD+ decline, increasing our likelihood of age-related diseases.
This is how the NAD+ precursor NMN also comes in. Some researchers feel that whenever we can restore that lost NAD+, we might not only decelerate aging but also delay various age-related diseases. Whether restoring NAD+ metabolism in humans will slow aging or support healthy longevity remains an unanswered question, although animal info is promising.
What foods contain NMN?
NMN is available naturally in foods including avocado, broccoli, cabbage, cucumber, and edamame. This is one way much NMN is located in some common foods.
While most of these foods are an excellent source of nutrition, dietary NMN supplements can also be found. These supplements typically are available in doses which can be between 100 – 500 mg, although an optimal dose has yet to be determined in people.
Fasting and caloric restriction also may actually increase NAD+ levels and raise the activity of sirtuins, aka the longevity genes. It is strongly recommended that the activity relies on a good NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, and yes it seems to decrease aging.
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